MS06 - OTHE-1 Griffin West Ballroom (#2133) in The Ohio Union
Modeling sex differences in health and disease
Thursday, July 20 at 10:30am
Sex hormones affect most, if not all, physiological systems. Historically, most physiological and biomedical research has largely been centered around males. In recent years, more sex-specific research has been conducted, revealing key structural and morphological differences in most organ systems between the sexes. Female physiology is complicated by the varied hormone levels that occur during the menstrual cycle as well as the massive changes during pregnancy/lactation or menopause. As we move towards precision medicine, to capture our diverse population we must attain a comprehensive understanding of the effects of sex-differences as well as the varied reproductive states in females on physiological function. Mathematical models have great potential to enhance our understanding of the effects of sex and reproductive states on physiological processes. By providing a quantitative framework for simulation and hypothesis testing, mathematical modeling and analysis can help untangle the complicated interactions of sexual dimorphisms or the impacts of varied reproductive states in anatomy, sex hormones, and physiological processes. In this mini-symposium speakers will present research using mathematical modeling to understand problems in health and disease related to sex differences or women’s health.