MS04 - ONCO-1 Ohio Staters Traditions Room (#2120) in The Ohio Union
Dynamics of cellular heterogeneity: consequences of diverse regulatory mechanisms
Tuesday, July 18 at 04:00pm
Mohit Kumar Jolly, Paras Jain
The advent of new experimental technologies and computational tools over past two decades have helped us to capture heterogeneity seen at the single-cell level. Further, the role of this heterogeneity in enabling a higher fitness of cancer cell population has been demonstrated. Moving ahead, a key focus is to understand the regulatory and stochastic origins of cellular heterogeneity so as to modulate it to achieve desired outcomes, such as better therapeutic outcomes. Here, we bring together a diverse set of experts who employ experimental and mathematical tools to understand the origins and consequences of heterogeneity witnessed in a cell population. Further, the symposium will also fuel the need to integrate information at multiple levels of intra-cellular/extra-cellular regulations to improve our understanding of functional responses at the single-cell/population levels.